Lidocaine-Heparin Bladder Instillation (Parson’s Solution)
Parson’s Solution can be used for alleviating painful symptoms associated with Interstitial Cystitis / Painful Bladder Syndrome (IC/PBS)
What is Parson’s Solution?
Parson’s Solution is a single vial solution for bladder instillation via an intravesical procedure involving instilling a therapeutic solution into the bladder to help treat the pain and other associated symptoms of IC/PBS. Parson’s Solution works by administering an absorbable form of the anaesthetic drug lidocaine (lignocaine), to potentially immediately reduce pain, along with high dose heparin, a component representative of bladder mucus, which may prevent further irritation of the bladder.
What are the benefits of Parson’s Solution?
The advantages of this instillation therapy are:
- The possible immediate relief of symptoms
- Possible minimal side effects
- Patients may not have to be admitted to hospital (can go home after the treatments)
- Convenient one use single vial dosage form
Parson’s Solution contains a per dose combination of 200 mg Lidocaine HCl and 50,000 Units Heparin Sodium, alkalinized using a specialized buffer system. This combination has been studied in placebo-controlled clinical studies where it has been shown to reduce pain quickly and provide over 12 hours of pain relief, after a single 45 minute instillation.
Parson’s Solution is available in the UK as an unlicensed “Specials” medicine on a named patient basis, distributed by Mawdsleys Specialty Pharmaceuticals.