Gepan®
What is Gepan® instill?
Gepan® instill is a pH-neutral, sterile solution which contains chondroitin sulphate (0.2%), a natural component of the protective layer of the bladder.
Gepan® instill is applied for the treatment of chronic forms of cystitis, e.g. interstitial cystitis, overactive bladder, radiation cystitis and chronically-recurring cystitis. These diseases are often associated with a damage of the glycosaminoglycan-layer of the bladder. The glycosaminoglycan-layer – or GAG-layer is a protective mucous membrane lining the bladder wall.
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Intact GAG-layer
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Damaged GAG-layer
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Gepan instill restored GAG-layer
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Therapy with Gepan® instill can improve symptoms and quality of life of patients by replenishing the glycosaminoglycan-layer – like a kind of liquid band aid on a wound.
What does Gepan® instill do?
Gepan® instill temporarily replaces the deficient GAG layer on the bladder wall. Gepan® instill can provide relief from distressing symptoms such as urgency, frequency and pain and improve quality of life in chronic forms of cystitis.
How is Gepan® instill administered?
Gepan® instill is instilled directly into the previously emptied bladder with the aid of a catheter. You should keep Gepan® instill in the bladder as long as possible, but for at least half an hour.
How long do I need treatment for?
The frequency of use and duration of treatment with Gepan® instill depend on the intensity of your symptoms. At the start of treatment, 4 to 6 instillations at weekly intervals have proved successful. Depending on your particular needs, your doctor may then adjust your therapy to one instillation per month.
Does Gepan® instill have any side-effects?
Research has shown that Gepan® instill is well tolerated and causes few, if any adverse reactions. Occasionally, some localised irritation has been experienced as a result of the instillation procedure itself, rather than as a side-effect of Gepan® instill.
How do I obtain treatment with Gepan® instill?
Gepan® instill requires administration by qualified medical personnel. Please ask your doctor (e.g. urologist or gynaecologist) if Gepan® instill is appropriate for your condition.
For more information: www.gepan-instill.com
