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Overactive Bladder

What is Overactive Bladder? Overactive bladder (OAB) is a common medical condition where the bladder muscle (detrusor) contracts too often or spontaneously and involuntarily. You may feel the need to pass urine more frequently and/or urgently than is necessary and some may also experience incontinence. Most commonly OAB is found in neurologically normal individuals. What Causes Overactive Bladder? It is not always easy to identify a common feature responsible for bladder over-activi
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IC Survey

To Date – Proposed New Survey No further survey of Interstitial Cystitis has been produced since 1999, so current statistic are a little unclear.  The COB Foundation is hoping to update their information and conduct a new survey of its members.  If you are interested in funding this work or helping with a proposal, please contact Alison Irving, Business Manager at COB Foundation: 0121 702 0820 If you wish to use our survey statistics for research or clinical studies, please cont
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Other Treatments

Bladder Distension/Bladder Stretch As well as a diagnostic procedure of IC/PBS, a bladder distention can also help to improve symptoms in some. A ‘Bladder Distention’ can be performed under general or local anaesthetic. The bladder is filled with sterile fluid and kept distended for 5-10 minutes. Directly after the procedure there may be some temporary bleeding or burning during urination. Some may experience a decrease in frequency and urgency soon after this, whilst others may have
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Parsons Solution

Lidocaine-Heparin Bladder Instillation (Parson’s Solution) Parson’s Solution can be used for alleviating painful symptoms associated with Interstitial Cystitis / Painful Bladder Syndrome (IC/PBS) What is Parson’s Solution? Parson’s Solution is a single vial solution for bladder instillation via an intravesical procedure involving instilling a therapeutic solution into the bladder to help treat the pain and other associated symptoms of IC/PBS. Parson’s Solution works by administering an
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Cystilieve

Cystilieve™ A NEW product may help patients with cystisis or painful bladder syndrome who have had no relief using other treatments.Cystilieve™ has been made available as a “special” – a product that can be ordered by doctors specially for named patients from Medicines By Design Ltd.Although Cystilieve™ is a novel formulation, the active ingredients – lidocaine and simple sodium bicarbonate – have been widely used for many years. Lidocaine solutions are already approved for local anaesthetic
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DMSO (Dimethyl Sulfoxide)

This treatment involves instilling DMSO into the bladder by a small catheter. Some patients find they have a garlic-like taste and odour for 1 or 2 days after treatment, this is due to the product odour being excreted through the lungs. Initially, there may be cystitis-like symptoms with urethral burning during voiding but these usually settle down within a day or two. The treatment is usually given for 6-8 weeks at fortnightly intervals. A catheter is placed into the bladder an
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Hyacyst®

What is Hyacyst®? Hyacyst® is a clear solution of sodium hyaluronate. The main ingredient is hyaluronic acid which occurs naturally throughout the body and bladder lining. Hyacyst® temporarily replaces hyaluronic acid and protects the bladder wall, reducing inflammation, promoting healing and creating a barrier against irritants in the urine. This helps to relieve the symptoms of pain, frequency and urgency of urination. Hyacyst® is available in a 40mg and 120mg strength in 50mls of solution
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IAluril®

What is iAluRil®? iAluRil is a medical device for the treatment of cases where the loss of components of the bladder lining causes chronic inflammation and infection. iAluRil can be used to treat: • Interstitial cystitis/painful bladder syndrome;• Chemical cystitis – damage to the bladder lining caused by chemotherapy;• Radiotherapy-induced cystitis – damage to the bladder lining caused by radiation to the pelvis;• Recurrent urinary tract infections.iAluRil work
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Uracyst®

What is Uracyst®? Uracyst® is a fluid that is instilled in to the bladder. It contains Sterile Sodium Chondroitin Sulfate Solution, 2.0%, and is effective in reducing the symtoms of interstitial cystitis/painful bladder syndrome (IC/PBS).What does Uracyst® do? Uracyst® works by replenishing the bladder with a protective coating of chondroitin sulfate, helping it to become waterproof again. Uracyst® reduces pain, frequency and urgency. How is Uracyst® administered? It is norm
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Gepan®

What is Gepan® instill?  Gepan® instill is a pH-neutral, sterile solution which contains chondroitin sulphate (0.2%), a natural component of the protective layer of the bladder.  Gepan® instill has been declared the favoured treatment in an independent scientific review (Madersbacher, 2013) for the treatment of chronic forms of cystitis, for example interstitial cystitis, overactive bladder, radiation cystitis and chronically recurring cystitis.  It is also recognised as an effective t
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